Type
Text
Type
Thesis
Advisor
Colognato, Holly | Martin, Benjamin
Date
2015-12-01
Keywords
Health sciences | Epidermolysis bullosa
Department
Department of Biochemistry and Cell Biology.
Language
en_US
Source
This work is sponsored by the Stony Brook University Graduate School in compliance with the requirements for completion of degree.
Identifier
http://hdl.handle.net/11401/76913
Publisher
The Graduate School, Stony Brook University: Stony Brook, NY.
Format
application/pdf
Abstract
The dysfunction of genes encoding integral proteins of the extracellular matrix and the basement membrane zone create foundations for the disease epidermolysis bullosa. Various proteins reside in the basement membrane zone and are responsible for the strength of the epidermal tissue. The cure for this disease is elusive which poses a problem for modern medicine. In this analysis, the mechanisms of epidermolysis bullosa subtypes were investigated and the viability of future treatment protocols was assessed. The promising treatment options include stem cell, gene, fibroblast, and protein therapy. Strategies need to be investigated further in order to develop therapeutic cures which will improve patient survival rates. | 32 pages
Recommended Citation
Dowling, Anna, "An Investigation of Epidermolysis Bullosa and an Analysis of Research and Treatment" (2015). Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions). 2786.
https://commons.library.stonybrook.edu/stony-brook-theses-and-dissertations-collection/2786