Type
Text
Type
Dissertation
Advisor
Luhmann, Christian C | Hajcak, Greg | Klein, Daniel N | Silk, Jennifer S | .
Date
2016-12-01
Keywords
Psychology | depression, development, EEG, event-related potential, reward, social
Department
Department of Clinical Psychology
Language
en_US
Source
This work is sponsored by the Stony Brook University Graduate School in compliance with the requirements for completion of degree.
Identifier
http://hdl.handle.net/11401/77178
Publisher
The Graduate School, Stony Brook University: Stony Brook, NY.
Format
application/pdf
Abstract
Depression represents a major public health concern, with particularly harmful effects in children. Existing interventions show relatively low response rates and high relapse rates, and there has been a recent effort to identify biomarkers of depression that may improve interventions and guide the way for novel treatments. One potential biomarker is the neural response to reward. However, existing studies typically focus on monetary reward, which may be less relevant to children and adolescents than social feedback. The current study focused on the feedback negativity (FN), an event-related potential (ERP) typically elicited by monetary feedback, in the context of a novel, ecologically valid social feedback task. The sample was composed of 213 8- to 16-year-old girls and parents. The goals of the study were to determine the degree of similarity between ERPs elicited by monetary and social feedback, and to assess unique relationships between the social FN and pubertal development, depression, and familial risk for depression when accounting for the response to monetary feedback. Although a robust FN response was not apparent in the ERP waveform for the social task, principal components analysis revealed an underlying component similar to the FN, which correlated strongly with the monetary FN and, unexpectedly, was larger for rejection compared to acceptance feedback. This component showed unique negative associations with latent variables representing both pubertal development and depression, and did not differ between participants at high and low familial risk for depression. The current results suggest that the social FN may reflect aspects of outcome salience in addition to reward value. The unique relationship between the social FN and depression, in the absence of an effect of maternal risk, indicates a possible role for the social FN as a state measure of decreased attentional engagement or emotional responsiveness in individuals with depression. Potential environmental influences on the relationship with pubertal development are also discussed. Although additional studies will be needed to further characterize the social FN, this component could serve as a useful measure of treatment response in future clinical studies. | 102 pages
Recommended Citation
Bress, Jennifer Nicole, "Response to monetary and social feedback during development: Associations with depressive symptomatology and risk" (2016). Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions). 3012.
https://commons.library.stonybrook.edu/stony-brook-theses-and-dissertations-collection/3012