Type
Text
Type
Dissertation
Advisor
Mohanty, Aprajita | Proudfit, Greg H | Luhmann, Christian | Patrick, Christopher.
Date
2014-12-01
Keywords
ERP, LPP, Neurobehavioral traits, Twin samples | Psychology
Department
Department of Clinical Psychology.
Language
en_US
Source
This work is sponsored by the Stony Brook University Graduate School in compliance with the requirements for completion of degree.
Identifier
http://hdl.handle.net/11401/77197
Publisher
The Graduate School, Stony Brook University: Stony Brook, NY.
Format
application/pdf
Abstract
Psychiatric disorders are the most common and costly forms of disease and injury worldwide. Despite this, our ability to accurately identify and treat these disorders is limited, due in part to deficient understanding of the underlying mechanisms of dysfunction. The current study aimed to identify genetically-influenced neurobehavioral traits--individual differences evident in both self-report and neural response--that might help improve classification and treatment of mental disorders. Results from event-related potential (ERP) components sensitive to emotional content demonstrated that a) neural processing of emotional content is heritable, b) the heritable traits of heightened trait fear and behavioral disinhibition are associated with unique emotional deficits measured by ERPs--high trait fear is associated with increased attention to threat, while behavioral disinhibition is associated with decreased attention to threat and reward, and c) the association between these heritable ERPs and self-reported traits is largely due to environmental influence. The results of this study should elucidate the pathways by which genes and environment interact to infl uence normal and abnormal behavior. | 106 pages
Recommended Citation
Weinberg, Anna EF, "Evidence for genetic contributions to neurobehavioral traits: Trait Fear/Fearlessness, Behavioral Inhibition, and the Late Positive Potential" (2014). Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions). 3031.
https://commons.library.stonybrook.edu/stony-brook-theses-and-dissertations-collection/3031