Type
Text
Type
Dissertation
Advisor
Button, Terry | Vaska, Paul | Schlyer, David J | Woody, Craig.
Date
2015-12-01
Keywords
Biomedical engineering
Department
Department of Biomedical Engineering
Language
en_US
Source
This work is sponsored by the Stony Brook University Graduate School in compliance with the requirements for completion of degree.
Identifier
http://hdl.handle.net/11401/76964
Publisher
The Graduate School, Stony Brook University: Stony Brook, NY.
Format
application/pdf
Abstract
Engineering in positron emission tomography contains within it a design for its application. The compact modular detector technology used in the Rat Conscious Animal PET (RatCAP) is specifically designed for awake rat imaging, but is versatile enough for its use in the construction of different preclinical systems. PET scanners based on the RatCAP system include the PET Insert for PET / MR Studies, the Whole-Body Rodent PET Scanner, the BNL PET Imaging System for Plant Science, and the Wrist PET Scanner. This dissertation concerns the development and characterization of these scanners, both specific to their particular use, and common in their architecture. A discussion of the signal processing hardware, and the data acquisition and processing methods that accompany it, designed to be robust and unified across all imaging systems, is included. These advances are applied for the calibration of each scanner, enabling the creation of images that contain quantitative information on various physiological functions. In addition, the performance of the Plant Scanner is evaluated, and examples from imaging studies using our scanners are shown. | 112 pages
Recommended Citation
Budassi, Michael, "Development and Characterization of High-Resolution Modular PET Imaging Systems" (2015). Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions). 2832.
https://commons.library.stonybrook.edu/stony-brook-theses-and-dissertations-collection/2832