Authors

Prafulla Keskar

Type

Text

Type

Thesis

Advisor

Sokolov, Jonathan | Rafailovich, Miriam | Gersappe, Dilip.

Date

2015-12-01

Keywords

Biochemistry

Department

Department of Materials Science and Engineering.

Language

en_US

Source

This work is sponsored by the Stony Brook University Graduate School in compliance with the requirements for completion of degree.

Identifier

http://hdl.handle.net/11401/76314

Publisher

The Graduate School, Stony Brook University: Stony Brook, NY.

Format

application/pdf

Abstract

The large number of devices used in medical applications have to be protected from microbial attacks as it leads to serious harm. Further, the current methods of tackling this problem involve using chemicals such as disinfectants which are harmful to us humans. This thesis aims to study the effectiveness of block copolymer thin films against microbes without using traditional harmful methods. We have attempted to prepare anti-bacterial thin films which can kill the bacteria using their surface morphology and thus eliminate the harm posed to us. In the second part of this thesis, we studied the growth characteristics of HeLa cells in hydrogel and the effect of titanium dioxide on them. HeLa cells are widely used in biomedical research and have played a key role in various scientific studies such as the development of polio vaccine. We prepared hydrogels of different concentrations and observed the growth of HeLa cells at different interval. | 29 pages

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